Despite being hated and feared by a world that doesn't understand them, the X-Men have sworn to use their powers to protect both humans and mutants. But with three simple words—"No More Mutants"—everything changed.

With mutantkind decimated and the the X-Men suffering devastating losses to their own ranks, they face an uncertain future. Fighting for their very existence against possible extinction, they now move from "Endangered Species" to "Messiah CompleX" at the most crucial point in their lives.