The FANTASTIC FOUR fall into a trap and are taken to the NEGATIVE ZONE, where they're attacked by ANNIHILUS and his warriors. But all is not as it seems - something in the Zone is affecting the Four's powers. Things go from bad to worse when DOCTOR DOOM arrives, apparently in league with Annihilus! But Doom isn't one to share power, and he takes Annihilus' energy source back to Earth with him. But even if the Four can escape Annihilus, how can they defeat Doom, who now has the power to destroy the world?