Superstar John Byrne's legendary run concludes with one of the most innovative periods in Fantastic Four history! The sensational She-Hulk replaces the Thing, Sue Richards becomes the Invisible Woman, and Mr. Fantastic is tried for crimes against the universe! Also featuring the return of Dr. Doom, the fate of Reed and Sue's unborn child, the resurrection of Jean Grey, and more - as the FF confront deadly foes including the Mole Man, Dr. Octopus, Terminus, the Beyonder, Mephisto, Psycho-Man and Annihilus! Plus: the unfinished "Last Galactus Story," reprinted for the first time! Collecting FANTASTIC FOUR (1961) #261-295 and ANNUAL #18-19, ALPHA FLIGHT (1983) #4, THING (1983) #10 and #19, and AVENGERS ANNUAL #14; and material from SECRET WARS II #2, EPIC ILLUSTRATED #26-34, WHAT IF? (1977) #36, WHAT THE-?! #2 and #10, THING (1983) #7, FANTASTIC FOUR ROAST, and FANTASTIC FOUR SPECIAL EDITION #1.