Mister Sinister turns his experimental talents on the Inhumans! Sinister has plagued the X-Men for years in his attempt to jump forward mutantkind's next evolutionary step. Now, he's looking to evolve the Inhumans - by kidnapping and torturing them! It's up to the Secret Warriors, the greatest team of Inhumans on Earth, to stop him. But what happens when their most fearsome warrior, Karnak, leaves to pursue his own agenda?