In ish #13, Blade conveyed his origin story... When his mother went into labor with him, it proved more difficult than her friends could handle, so they called a doctor. This man turned out to be a vampire who bit his mother after sending the other women away. Her screams drew their attention, though, and they managed to chase the creature off.
Blade's mother died in labor, but the unique circumstances of his birth gave him not only a monster to hunt, but also made him resistant to a vampire's bite and hypnotic abilities. Years later, in 1999's PETER PARKER: SPIDER-MAN #7-8, the scientifically created Morbius bit Blade, which resulted in the vampire hunter gaining many of his prey's abilities—and a few of the weaknesses.
Since first making his presence felt over 40 years ago, Blade's made quite an impression on the world. He's starred in solo and team books and made a great deal of guest appearances. And now, with his appearances in AVENGERS (2018) and STRIKEFORCE, he's ready to thrill fans all over again.